Monthly Archives: December 2012

The Road Map for European Ageing Research: a source of inspiration for PredSL

Road mapThe Road Map for European Ageing Research was drafted last year by the FUTURAGE project and contains the research agenda that will enable Europe to respond successfully to the unprecedented demographic challenges it faces. The Road Map priority themes for future ageing research are all based on eight fundamental assumptions: multi-disciplinarity, user engagement, a life course perspective, a person-environment perspective, the importance of diversities and intergenerational relationships, knowledge exchange and technological innovation. PredSL links two Road Map priority themes: Maintaining and regaining mental capacity and Inclusion and participation in the community and in the labour market.

Cochrane review on interventions to facilitate return to work

PredSL PI Ute Bültmann contributed to a Cochrane Review on interventions to facilitate return to work in adults with adjustment disorders that was published today.

Adjustment disorders are a frequent cause of sick leave and various interventions have been developed to expedite the return to work (RTW) of individuals on sick leave due to adjustment disorders. The review assesses the effects of interventions facilitating RTW for workers with acute or chronic adjustment disorders and discusses results from nine studies reporting on 10 psychological interventions and one combined intervention in 1546 participants.


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Cortisol and anxiety and depressive problems – results from TRAILS

PredSL PI Catharina Hartman contributed to  a study – that was published today in Psychoneuroendocrinology – on the relationship between anxiety and depressive problems and hypothalamic-pituitary-adrenal (HPA)-axis activity (cortisol in the morning). The study was executed in children from the TRAILS study, a general population and clinic-referred cohort.

Anxiety and depressive problems have often been related to higher hypothalamic-pituitary-adrenal (HPA)-axis activity (basal morning cortisol levels and cortisol awakening response [CAR]) and externalizing problems to lower HPA-axis activity. However, associations appear weaker and more inconsistent than initially assumed. Previous studies from TRAILS suggested sex-differences in these relationships and differential associations with specific dimensions of depressive problems in a general population sample of children (10-12 years). Using the TRAILS population sample (n=1604), the authors found most support for higher cortisol (mainly CAR) in relation to depressive problems. However, in general, associations were weak. Therefore, the present results shed doubt on the relevance of single day cortisol measurements for problem behaviors in the milder range. Associations may be stronger in more severe or persistent psychopathology.

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